The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2021
Filed:
Aug. 08, 2019
Jiangsu Academy of Agricultural Sciences, Nanjing, CN;
Xianjin Liu, Jiangsu, CN;
Yajing Xie, Jiangsu, CN;
Chongxin Xu, Jiangsu, CN;
Xiao Zhang, Jiangsu, CN;
Meijing Gao, Jiangsu, CN;
Xin He, Jiangsu, CN;
Yuan Liu, Jiangsu, CN;
Cunzheng Zhang, Jiangsu, CN;
Jiangsu Academy of Agricultural Sciences, Jiangsu, CN;
Abstract
The present invention provides a human-derived molecularly modified insecticidal protein, and a preparation method and application thereof, and belongs to the field of genetic engineering and biological control. The present invention provides a human-derived molecularly modified insecticidal protein, and the amino acid sequence of the insecticidal protein CCL-CCL_scFv is shown as SEQ ID No. 1. The insecticidal protein CCL-CCL_scFv shows significantly higher affinity with midgut BBMV ofthan Cry1Ab toxin, competes with Cry1Ab and Cry1Ac toxins for binding the midgut BBMV of, and is a mimic of Cry1Ab and Cry1Ac toxins. Throughindoor insecticidal biological activity assay, the insecticidal protein shows a good insecticidal effect, and can effectively replace Cry1Ac or Cry1Ab toxin for biological control of insect pest.