The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 2021

Filed:

Dec. 07, 2020
Applicant:

Think Therapeutics, Inc., Newton, MA (US);

Inventors:

David Gifford, Newton, MA (US);

Brandon Carter, Cambridge, MA (US);

Assignee:

Think Therapeutics, Inc., Newton, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/74 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01); G16B 20/30 (2019.01); G16B 30/00 (2019.01); G16B 35/10 (2019.01); G16B 20/40 (2019.01); G16B 5/20 (2019.01); G16B 15/20 (2019.01); G16B 5/00 (2019.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70539 (2013.01); A61K 39/0011 (2013.01); G01N 33/56977 (2013.01); G16B 5/00 (2019.02); G16B 5/20 (2019.02); G16B 15/20 (2019.02); G16B 20/30 (2019.02); G16B 20/40 (2019.02); G16B 30/00 (2019.02); G16B 35/10 (2019.02); A61K 38/00 (2013.01);
Abstract

A system for selecting an immunogenic peptide composition comprising a processor and a memory storing processor-executable instructions that, when executed by the processor, cause the processor to create a first peptide set by selecting a plurality of base peptides, wherein at least one peptide of the plurality of base peptides is associated with a disease, create a second peptide set by adding to the first peptide set a modified peptide, wherein the modified peptide comprises a substitution of at least one residue of a base peptide selected from the plurality of base peptides, and create a third peptide set by selecting a subset of the second peptide set, wherein the selected subset of the second peptide set has a predicted vaccine performance, wherein the predicted vaccine performance has a population coverage above a predetermined threshold, and wherein the subset comprises at least one peptide of the second peptide set.


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