The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2021
Filed:
May. 24, 2018
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Robert H. Mach, Wallingford, PA (US);
Sean Reilly, Philadelphia, PA (US);
Mehran Makvandi, Philadelphia, PA (US);
Kuiying Xu, Wallingford, PA (US);
Daniel A. Pryma, Bryn Mawr, PA (US);
Roger A. Greenberg, Bala Cynwyd, PA (US);
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Abstract
The present disclosure relates to compounds of Formula I and II, wherein R-Rand FL are defined herein. Also provided are methods of targeting alpha-radiation to poly(ADP-ribose)polymerase 1 (PARP-1) enzyme expression, reducing proliferation of cancer cells, reducing proliferation of cancer cells, detecting intact and enzymatically active poly(ADP-ribose)polymerase 1 (PARP-1) enzyme expression, detecting PARP-1 enzyme expression in a subjects tissue sample, monitoring cancer treatment in a subject, or detecting a PARP-1 receptive cancer in a subject.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile