The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2021
Filed:
Mar. 01, 2018
Pfizer Inc., New York, NY (US);
Thomas Allen Chappie, Carlisle, MA (US);
Paul Galatsis, Newton, MA (US);
Michelle Renee Garnsey, Providence, RI (US);
Christopher John Helal, Mystic, CT (US);
Jaclyn Louise Henderson, Cambridge, MA (US);
Bethany Lyn Kormos, Somerville, MA (US);
Ravi G. Kurumbail, East Lyme, CT (US);
Luis Angel Martinez-Alsina, Gales Ferry, CT (US);
Martin Youngjin Pettersson, Littleton, MA (US);
Antonia Friederike Stepan, Biberach an der Riss, DE;
Travis T. Wager, Brookline, MA (US);
PFIZER INC., New York, NY (US);
Abstract
The present invention provides novel cyclic substituted imidazo[4,5-c]quinoline derivatives of Formula (I), and the pharmaceutically acceptable salts thereof; wherein R, R, R, R, R, X and Z are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising the compounds of Formula I and to use of the compounds in the treatment of diseases associated with LRRK2, such as neurodegenerative diseases including Parkinson's disease or Alzheimer's disease, cancer, Crohn's disease or leprosy.