logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11161824 B1

PDFFull Text
Date of Patent:
Nov. 02, 2021

Filed:

Aug. 18, 2017

Heterocyclic lipoxin analogs and uses thereof

Applicant:

University College Dublin, National University of Ireland, Dublin, Dublin, IE;

Inventors:

Patrick Guiry, Dublin, IE;

Catherine Godson, Dublin, IE;

Monica De Gaetano, Dublin, IE;

Eibhlin Butler, Dublin, IE;

Claire Wilson, Dublin, IE;

Catherine Tighe, Dublin, IE;

Denise Moran, Dublin, IE;

Andrea Zanetti, Dublin, IE;

Kevin Gahan, Dublin, IE;

Assignee:

University College Dublin, National University of Ireland, Dublin, Dublin, IE;

Attorney:

Hoffman Warnick LLC

Primary Examiner:

Bruck Kifle

Int. Cl.
CPC ...
C07D 239/26 (2006.01); C07D 215/14 (2006.01); C07D 217/02 (2006.01); C07D 239/74 (2006.01); C07D 241/42 (2006.01); C07D 231/12 (2006.01); C07D 307/36 (2006.01); C07D 307/79 (2006.01); C07D 333/06 (2006.01); A61K 31/341 (2006.01); A61K 31/343 (2006.01); A61K 31/381 (2006.01); A61K 31/40 (2006.01); A61K 31/404 (2006.01); A61K 31/47 (2006.01); A61K 31/472 (2006.01); A61P 11/06 (2006.01); A61P 13/12 (2006.01); C07D 215/18 (2006.01); C07D 217/22 (2006.01); C07D 233/68 (2006.01); C07D 263/32 (2006.01); C07D 263/34 (2006.01); C07D 307/80 (2006.01); C07D 333/56 (2006.01); C07D 405/06 (2006.01); C07D 407/06 (2006.01); C07D 409/06 (2006.01); C07D 413/06 (2006.01);
U.S. Cl.
CPC ...
C07D 241/42 (2013.01); C07D 215/14 (2013.01); C07D 215/18 (2013.01); C07D 217/22 (2013.01); C07D 233/68 (2013.01); C07D 263/32 (2013.01); C07D 263/34 (2013.01); C07D 307/80 (2013.01); C07D 333/56 (2013.01); C07D 405/06 (2013.01); C07D 407/06 (2013.01); C07D 409/06 (2013.01); C07D 413/06 (2013.01);
Abstract

The present invention relates to a compound of formula (I): wherein L is an optionally substituted heterocyclic group excluding unsubstituted monocyclic pyridine groups; wherein a is 0, 1 or 2; wherein Ris H or with Ris a bond; wherein Ris an optionally substituted alkoxy or aryloxy group, or with Rforms a bond; wherein Ris an optionally substituted alkyl group; and wherein Ris CH, CMeor O. Such compounds may be used in the treatment or prophylaxis of a disease or condition in which inhibition of acute inflammation and/or promotion of its resolution and/or suppression of fibrosis.

Find Patent Forward Citations

Loading…