The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 2021

Filed:

May. 25, 2017
Applicant:

Integrated Micro-chromatography Systems, Inc., Irmo, SC (US);

Inventors:

Brian Todd Mullis, Columbia, SC (US);

Gary Horvath, Columbia, SC (US);

Lim Andrew Lee, Columbia, SC (US);

Sunil Hwang, Charlotte, NC (US);

William Edward Brewer, Columbia, SC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/02 (2006.01); G01N 1/40 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
B01L 3/0275 (2013.01); C12N 15/101 (2013.01); C12N 15/1006 (2013.01); C12N 15/1017 (2013.01); G01N 1/405 (2013.01); B01L 2200/0631 (2013.01); B01L 2300/069 (2013.01); B01L 2300/12 (2013.01);
Abstract

The present invention provides a disposable pipette tip for dispersive solid phase extraction (SPE) that allows for rapid, automatable purification of large biomolecules, such as nucleic acids, proteins and polypeptides without the need for additional tools such as centrifuges, magnetic plates or vacuum manifolds. The pipette tip is designed for optimal biomolecule isolation while maintaining sample integrity. Optimized methods of using the dispersive pipette extraction system for isolation of large biomolecules are also provided.


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