The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 2021

Filed:

Oct. 26, 2018
Applicant:

National Health Research Institutes, Zhunan Town, TW;

Inventors:

Ming-Hsi Huang, Zhunan Town, TW;

Chung-Hsiung Huang, Zhunan Town, TW;

Chiung-Yi Huang, Zhunan Town, TW;

Assignee:

NATIONAL HEALTH RESEARCH INSTITUTES, Zhunan Township, Miaoli County, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/39 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61P 35/00 (2018.01); A61K 2039/543 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/585 (2013.01);
Abstract

The invention provides a nanoemulsion adjuvant and a preparation method thereof, which are composed of the following components: a continuous aqueous phase containing HO molecules, an oil phase material containing fats and oils, and an emulsion system for stabilizing the interface between the continuous aqueous phase and the oil phase, and the emulsion system is an emulsifier mixture. The adjuvant is characterized in that the emulsion system does not contain an ionic emulsifier and the particle size of the emulsion is between 20 and 200 nanometers. The use of the nanoemulsion adjuvant can prevent toxicity and possible harm of ionic emulsifiers to human cells, and provide a vaccine preparation capable of eliciting a high degree of immune response.


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