The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2021
Filed:
Nov. 30, 2017
Industry-academic Cooperation Foundation, Yonsei University, Seoul, KR;
Cosmax Nbt, Inc., Seoul, KR;
Cosmax Ns, Inc., Seoul, KR;
Jae Kwan Hwang, Seoul, KR;
Jun Gon Yun, Seoul, KR;
Mi Bo Kim, Seoul, KR;
Chang Hee Kim, Seoul, KR;
Joon Hyung Lee, Seoul, KR;
Do Wan Kwon, Gyeongsangbuk-do, KR;
Su Young Choi, Gyeonggi-do, KR;
Jin Hak Kim, Seoul, KR;
Ji Hwan Jang, Gyeonggi-do, KR;
Jeong Ho Geum, Seoul, KR;
Min Son Kweon, Seoul, KR;
Industry-Academic Cooperation Foundation, Yonsei University, Seoul, KR;
Cosmax NBT, Inc., Seoul, KR;
Cosmax NS, Inc., Seoul, KR;
Abstract
The present invention relates to a composition for preventing or treating a muscle disorder, which includes a chrysanthemum extract or 3,5-dicaffeoylquinic acid as an active ingredient, and specifically, it may be used to reduce mRNA expression of atrogin-1 and MuRF1, which are main biomarkers involved in muscle protein degradation and increase mRNA expression of the mTOR protein, which is a main biomarker involved in muscle protein formation, and myogenin and MyoD, which are biomarkers related to muscle differentiation, thereby reducing muscle loss, and thus the chrysanthemum extract or 3,5-dicaffeoylquinic acid can be used in prevention and treatment of a muscle disorder, or improvement in muscle function. In addition, the chrysanthemum extract or 3,5-dicaffeoylquinic acid increases the activity of SIRT1 and PGC-1α, which are the main biomarkers involved in exercise performance, thereby excellently enhancing exercise performance. In addition, the present invention is a natural substance and may be safely used without a side effect, and therefore may be used as a medication, food or a cosmetic.