The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 2021

Filed:

Apr. 10, 2015
Applicant:

Université Catholique DE Louvain, Louvain la Neuve, BE;

Inventors:

Pierre Gianello, Rixensart, BE;

Nizar Mourad, Brussels, BE;

Assignee:

UNIVERSITÉ CATHOLIQUE DE LOUVAIN, Louvain la Neuve, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/39 (2015.01); A61K 35/12 (2015.01); A01K 67/027 (2006.01); A61K 9/06 (2006.01); A61K 38/26 (2006.01); C07K 14/605 (2006.01); C12N 5/071 (2010.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A61K 35/39 (2013.01); A01K 67/0275 (2013.01); A61K 9/06 (2013.01); A61K 38/26 (2013.01); C07K 14/605 (2013.01); C12N 5/0677 (2013.01); C12N 15/8509 (2013.01); A01K 2207/12 (2013.01); A01K 2217/072 (2013.01); A01K 2227/108 (2013.01); A01K 2267/00 (2013.01); A61K 2035/128 (2013.01); C12N 2015/8536 (2013.01);
Abstract

The present invention relates to an isolated transgenic pig beta cell wherein the PKC and the PKA pathway are constitutively activated; to a transgenic pig islet comprising said transgenic pig beta cell; and to a transgenic pig comprising said transgenic pig beta cell or said transgenic pig islet. Another object of the invention is a device comprising a transgenic pig beta cell or a transgenic pig islet of the invention. The present invention also relates to the use of said transgenic pig beta cell, said transgenic pig islet, or said device for treating a disease, disorder or condition related to the impaired function of endocrine pancreas or of beta cell.


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