The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 2021

Filed:

Oct. 18, 2019
Applicant:

Theravance Biopharma R&d Ip, Llc, South San Francisco, CA (US);

Inventors:

Robert Murray McKinnell, Millbrae, CA (US);

Venkat R. Thalladi, Foster City, CA (US);

Hao Zhang, Foster City, CA (US);

Paul R. Fatheree, San Francisco, CA (US);

Lan Jiang, Foster City, CA (US);

Marta Dabros, Foster City, CA (US);

Jerry Nzerem, South San Francisco, CA (US);

Assignee:

Theravance Biopharma R&D IP, LLC, South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 9/10 (2006.01); A61K 9/00 (2006.01); A61P 29/00 (2006.01); A61P 11/08 (2006.01); A61P 17/04 (2006.01); A61P 27/02 (2006.01); A61P 11/06 (2006.01); C07D 471/04 (2006.01); A61P 11/00 (2006.01); A61P 17/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 9/0019 (2013.01); A61K 9/0048 (2013.01); A61K 9/10 (2013.01); A61P 11/00 (2018.01); A61P 11/06 (2018.01); A61P 11/08 (2018.01); A61P 17/00 (2018.01); A61P 17/04 (2018.01); A61P 27/02 (2018.01); A61P 29/00 (2018.01); C07D 471/04 (2013.01);
Abstract

The invention provides a compound of formula 1 or a pharmaceutically-acceptable salt thereof, that is useful as a JAK inhibitor. The invention also provides crystalline forms of the compound, pharmaceutical compositions comprising the compound, methods of using the compound to treat diseases amenable to a JAK inhibitor, and processes and intermediates useful for preparing the compound.


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