The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 2021

Filed:

Apr. 11, 2018
Applicant:

The George Washington University, a Congressionally Chartered Not-for-profit Corporation, Washington, DC (US);

Inventors:

Chi-Wei Chen, Silver Spring, MD (US);

Yongming Li, Liaoning, CN;

Zhiyong Han, Fairfax, VA (US);

Wenge Zhu, Germantown, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7064 (2006.01); A61K 31/28 (2006.01); A61K 31/05 (2006.01); A61P 35/00 (2006.01); A61K 33/243 (2019.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/05 (2013.01); A61K 33/243 (2019.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract

The present disclosure provides methods, pharmaceutical compositions, dosing regimens, and kits comprising 4,4'-trans-dihydroxystilbene (DHS), including methods of treating cancer in a subject and methods of decreasing or reversing resistance to a DNA damaging agent in a subject.


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