The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2021

Filed:

Aug. 08, 2018
Applicant:

California Institute of Technology, Pasadena, CA (US);

Inventors:

Haowen Ruan, Pasadena, CA (US);

Jacob Berlin, Duarte, CA (US);

Tom Haber, Duarte, CA (US);

Changhuei Yang, South Pasadena, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/47 (2006.01); G03H 1/04 (2006.01); G01N 33/483 (2006.01); G03H 1/22 (2006.01); G03H 1/00 (2006.01);
U.S. Cl.
CPC ...
G03H 1/0443 (2013.01); G01N 21/4795 (2013.01); G01N 33/4833 (2013.01); G03H 1/0005 (2013.01); G03H 1/0465 (2013.01); G03H 1/2294 (2013.01); G03H 2001/0083 (2013.01); G03H 2001/0447 (2013.01); G03H 2001/0458 (2013.01); G03H 2001/0471 (2013.01); G03H 2225/30 (2013.01);
Abstract

A magnetic field controlled guidestar for focusing light deep inside scattering media using optical phase conjugation. Compared with the optical and ultrasonic field, the magnetic field has an exceptional penetration depth. The magnetic particle guidestar has a high light-tagging efficiency, good biocompatibility, and a small diameter which enables a sharp and bright focusing deep inside biological tissue. This new method can benefit a wide range of biomedical applications including deep-tissue imaging, neural modulation, and targeted photothermal and photodynamic therapies.


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