The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
Sep. 07, 2018
Applicant:
Liposcience, Inc., Morrisville, NC (US);
Inventors:
James D. Otvos, Cary, NC (US);
Irina Y. Shalaurova, Cary, NC (US);
Assignee:
LipoScience, Inc., Morrisville, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/92 (2006.01); G01R 33/465 (2006.01); G16H 10/40 (2018.01); G16H 50/30 (2018.01); A61B 5/055 (2006.01); G16H 50/50 (2018.01); A61B 5/00 (2006.01); G16Z 99/00 (2019.01); G16B 20/00 (2019.01); G16C 20/20 (2019.01);
U.S. Cl.
CPC ...
G01N 33/92 (2013.01); A61B 5/055 (2013.01); A61B 5/7275 (2013.01); G01R 33/465 (2013.01); G16H 10/40 (2018.01); G16H 50/30 (2018.01); G16H 50/50 (2018.01); G16Z 99/00 (2019.02); G01N 2800/32 (2013.01); G16B 20/00 (2019.02); G16C 20/20 (2019.02);
Abstract
Disclosed are methods and systems to determine a subject's metabolic vulnerability index (MVX) score using at least one defined mathematical model of risk. The methods comprise evaluating various biomarkers to distinguish various health risks. In one embodiment, the method comprises evaluating biomarkers to determine a relative risk of premature all-cause mortality. The model may include NMR-derived measurements of GlycA, S-HDLP, branched chain amino acids (BCAAs), ketone bodies, total serum protein, and citrate in at least one biosample of the subject.