The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
Feb. 09, 2016
Biontech Rna Pharmaceuticals Gmbh, Mainz, DE;
Tron-translationale Onkologie an Der Universitätsmedizin Der Johannes Gutenberg-universität Mainz Ggmbh, Mainz, DE;
Ugur Sahin, Mainz, DE;
Martin Löwer, Mainz, DE;
Arbel D. Tadmor, Bodenheim, DE;
Sebastian Boegel, Obermoschel, DE;
Barbara Schrörs, Mainz, DE;
Mathias Vormehr, Mainz, DE;
Sebastian Kreiter, Mainz, DE;
Abstract
The present invention relates to methods for predicting T cell epitopes useful for vaccination. In particular, the present invention relates to methods for predicting whether modifications in peptides or polypeptides such as tumor-associated neoantigens are immunogenic and, in particular, useful for vaccination, or for predicting which of such modifications are most immunogenic and, in particular, most useful for vaccination. The methods of the invention may be used, in particular, for the provision of vaccines which are specific for a patient's tumor and thus, in the context of personalized cancer vaccines.