The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2021

Filed:

Aug. 22, 2017
Applicant:

Sensor Kinesis Corporation, Los Angeles, CA (US);

Inventors:

Yehoshua Shachar, Santa Monica, CA (US);

Roger Kornberg, Atherton, CA (US);

Assignee:

Autonomous Medical Devices Inc., Santa Monica, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/06 (2006.01); G01N 29/22 (2006.01); G01N 29/34 (2006.01); B81C 1/00 (2006.01); G01N 29/036 (2006.01); G01N 29/02 (2006.01); C12N 15/10 (2006.01); G01N 33/53 (2006.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
G01N 15/0606 (2013.01); B81C 1/00206 (2013.01); C12N 15/1037 (2013.01); G01N 29/022 (2013.01); G01N 29/036 (2013.01); G01N 29/222 (2013.01); G01N 29/348 (2013.01); G01N 33/5306 (2013.01); B81B 2201/0214 (2013.01); B81C 2201/0149 (2013.01); G01N 2015/0065 (2013.01); G01N 2291/0255 (2013.01); G01N 2291/0256 (2013.01); G01N 2291/0423 (2013.01);
Abstract

A surface acoustic wave (SAW) performs a rapid, label-free detection of biological species. Biosensing and detection of multiple analytes multiplexed by an array of sensing lanes is configured to enable bio-amplification using engineered DNA encoded libraries as the probe through a phage display procedure to enhance specificity, capture statistics for the detection, screening and analyzing of the analyte in vitro. A biochemical formulation minimizes the limit of detection (LOD) at a threshold magnitude on the order of a femtomolar concentration. Additional enhancement of the apparatus is achieved by use of an analog front end to amplify biochemical events.


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