The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2021

Filed:

Mar. 18, 2020
Applicant:

Modular Genetics, Inc., Woburn, MA (US);

Inventors:

Kevin A. Jarrell, Lincoln, MA (US);

Gabriel O. Reznik, Bedford, MA (US);

Prashanth Vishwanath, Arlington, MA (US);

Michelle Pynn, Andover, MA (US);

Assignee:

Modular Genetics, Inc., Woburn, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/80 (2006.01); C12P 13/02 (2006.01); C12N 9/00 (2006.01); A01N 37/36 (2006.01); C07C 235/06 (2006.01);
U.S. Cl.
CPC ...
C12P 13/02 (2013.01); A01N 37/36 (2013.01); C07C 235/06 (2013.01); C12N 9/80 (2013.01); C12N 9/93 (2013.01); C12Y 603/02 (2013.01);
Abstract

In certain embodiments, the present invention comprises compositions and methods useful in the generation of acyl amino acids. In certain embodiments, the present invention provides an engineered polypeptide comprising a peptide synthetase domain; in some such embodiments, the engineered polypeptide comprises only a single peptide synthetase domain. In some embodiments, the present invention provides an engineered peptide synthetase that is substantially free of a thioesterase domain, and/or a reductase domain. In certain embodiments, the present invention provides an acyl amino acid composition comprising a plurality of different forms of an acyl amino acid. In some such compositions, substantially all of the acyl amino acids within the composition contain the same amino acid moiety and differ with respect to acyl moiety. We also described populations where the fatty acid si for example 95% one length (C14, myristic).


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