The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
Mar. 13, 2018
Applicant:
International Centre for Genetic Engineering and Biotechnology—icgeb, Trieste, IT;
Inventors:
Mauro Giacca, Trieste, IT;
Luca Braga, Trieste, IT;
Matteo Dal Ferro, Trieste, IT;
Miguel Luis Cunha Mano, Coimbra, PT;
Ana Sofia Bregieiro Eulalio, Coimbra, PT;
Assignee:
KING'S COLLEGE LONDON, London, GB;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/86 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 15/86 (2013.01); C12N 2310/141 (2013.01); C12N 2750/14143 (2013.01);
Abstract
The present invention refers to human microRNA hsa-miR-665 for the treatment or prevention of heart diseases associated with cardiac hypertrophy and consequent pathological remodeling of the heart, in particular for preventing and/or treating heart failure (HF). Vectors and pharmaceutical compositions comprising said miRNA for the disclosed uses are also within the scope of the present invention.