The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2021

Filed:

Feb. 21, 2017
Applicant:

Caribou Biosciences, Inc., Berkeley, CA (US);

Inventors:

Daniel Capurso, Weatogue, CT (US);

Andrew P. May, San Francisco, CA (US);

Megan Van Overbeek, Oakland, CA (US);

Assignee:

Caribou Biosciences, Inc., Berkeley, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 15/11 (2006.01); C12N 15/90 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); C12N 15/102 (2013.01); C12N 15/90 (2013.01); C12N 15/902 (2013.01); C12N 15/907 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract

Methods for gene editing and predicting non-random editing events are described. The methods use Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems to characterize and manipulate DNA repair outcomes at Cas-initiated double-strand breaks (DSBs) to anticipate functional outcomes.


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