The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2021

Filed:

Dec. 18, 2020
Applicant:

Beam Therapeutics Inc., Cambridge, MA (US);

Inventors:

Nicole Gaudelli, Cambridge, MA (US);

Michael Packer, Cambridge, MA (US);

Ian Slaymaker, Cambridge, MA (US);

Yi Yu, Cambridge, MA (US);

Bernd Zetsche, Cambridge, MA (US);

Jason Michael Gehrke, Cambridge, MA (US);

Natalie Petrossian, Cambridge, MA (US);

Angelica Messana, Cambridge, MA (US);

Yvonne Aratyn, Cambridge, MA (US);

Francine Gregoire, Cambridge, MA (US);

Genesis Lung, Cambridge, MA (US);

Shaunna Berkovitch, Cambridge, MA (US);

David A. Born, Cambridge, MA (US);

Seung-Joo Lee, Cambridge, MA (US);

Assignee:

BEAM THERAPEUTICS INC., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/78 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); A61P 43/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/78 (2013.01); A61P 43/00 (2018.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12Y 305/04004 (2013.01); C07K 2319/09 (2013.01); C07K 2319/80 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract

The disclosure provides compositions comprising novel adenosine base editors (e.g., ABE8) that have increased efficiency and methods of using these adenosine deaminase variants for editing a target sequence.


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