The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
Sep. 05, 2019
Applicant:
The Rockefeller University, New York, NY (US);
Inventors:
Vincent A. Fischetti, New York, NY (US);
Jonathan Schmitz, New York, NY (US);
Daniel Gilmer, New York, NY (US);
Chad Euler, New York, NY (US);
Assignee:
THE ROCKEFELLER UNIVERSITY, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/36 (2006.01); A61K 38/16 (2006.01); A61K 38/50 (2006.01); A61K 38/47 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2462 (2013.01); A61K 38/162 (2013.01); A61K 38/47 (2013.01); A61K 38/50 (2013.01); A61K 45/06 (2013.01); C12Y 302/01017 (2013.01);
Abstract
The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, includingand, and related conditions. The invention provides compositions and methods incorporating and utilizingderived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided.