The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
Dec. 19, 2016
Applicant:
Psioxus Therapeutics Limited, Abingdon, GB;
Inventors:
Alice Claire Noel Brown, Abingdon, GB;
Brian Robert Champion, Abingdon, GB;
Assignee:
PSIOXUS THERAPEUTICS LIMITED, Abingdon, GB;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 35/761 (2015.01); A61K 38/17 (2006.01); C07K 14/00 (2006.01); A61K 35/768 (2015.01); A61P 35/00 (2006.01); C07K 14/005 (2006.01); C07K 14/725 (2006.01); C07K 16/30 (2006.01); C12N 7/00 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2809 (2013.01); A61K 35/761 (2013.01); A61K 35/768 (2013.01); A61K 38/1774 (2013.01); A61P 35/00 (2018.01); C07K 14/00 (2013.01); C07K 14/005 (2013.01); C07K 14/7051 (2013.01); C07K 16/2803 (2013.01); C07K 16/30 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 2039/505 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C12N 2710/10032 (2013.01); C12N 2710/10041 (2013.01);
Abstract
The present disclosure relates to a replication deficient oncolytic viral vector or replication capable oncolytic virus encoding an antibody or a binding fragment thereof to the antigen-specific T-cell receptor complex (TCR) for expression on the surface of a cancer cell, pharmaceutical compositions comprising the same, and use of any one of the same in treatment, particularly in the treatment of cancer.