The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
Jul. 24, 2019
Medimmune, Llc, Gaithersburg, MD (US);
Humabs Biomed SA, Bellinzona, CH;
Christine Tkaczyk, Gaithersburg, MD (US);
Bret Sellman, Gaithersburg, MD (US);
Martin Borrok, III, Gaithersburg, MD (US);
Davide Corti, Bellinzona, CH;
Andrea Minola, Bellinzona, CH;
MedImmune, LLC, Gaithersburg, MD (US);
Humabs BioMed SA, Bellinzona, CH;
Abstract
The present disclosure is directed to a monoclonal antibody, or antigen-binding fragment thereof, that specifically binds to aclumping factor A protein (ClfA), as well as compositions comprising the monoclonal antibody. The disclosure also is directed to methods of treating ainfection by administering the anti-ClfA monoclonal antibody alone, or in combination with a monoclonal antibody that specifically binds toalpha toxin (AT) protein to a subject. Bispecific monoclonal antibodies that specifically bind to both ClfA and AT and methods of using the same also are provided.