The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2021

Filed:

Dec. 16, 2019
Applicant:

The Usa, As Represented BY the Secretary, Dept. of Health and Human Services, Bethesda, MD (US);

Inventors:

Jeffrey Schlom, Potomac, MD (US);

Kwong-Yok Tsang, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07K 14/82 (2006.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); A61K 38/21 (2006.01); A61K 38/22 (2006.01); A61K 31/00 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); C12N 7/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4727 (2013.01); A61K 31/00 (2013.01); A61K 38/191 (2013.01); A61K 38/193 (2013.01); A61K 38/195 (2013.01); A61K 38/20 (2013.01); A61K 38/217 (2013.01); A61K 38/22 (2013.01); A61K 39/00117 (2018.08); A61K 39/39 (2013.01); A61K 45/06 (2013.01); C07K 14/82 (2013.01); C12N 7/00 (2013.01); A61K 38/00 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55588 (2013.01); C07K 2319/00 (2013.01); C12N 2710/24143 (2013.01); C12N 2710/24171 (2013.01);
Abstract

The invention provides a human cytotoxic T lymphocyte (CTL) agonist epitope from the C-terminal subunit of mucin 1 (MUC1-C), which can be used as a peptide, polypeptide (protein), and/or in vaccine or other composition for the prevention or therapy of cancer. The invention further provides a nucleic acid encoding the peptide, protein, or polypeptide, a vector comprising the nucleic acid, a cell comprising the peptide, polypeptide, nucleic acid, or vector, and compositions thereof.


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