The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2021

Filed:

Jun. 22, 2016
Applicant:

University of Utah Research Foundation, Salt Lake City, UT (US);

Inventors:

Danny Hung-Chieh Chou, Salt Lake City, UT (US);

Yuanxiang Wang, Salt Lake City, UT (US);

Assignee:

University of Utah Research Foundation, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/113 (2006.01); C07K 14/605 (2006.01); C07K 7/06 (2006.01); C07K 7/56 (2006.01); C07K 1/00 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); C07K 1/006 (2013.01); C07K 1/1133 (2013.01); C07K 7/56 (2013.01); C07K 14/4748 (2013.01); C07K 14/605 (2013.01);
Abstract

In one aspect, the invention relates to compositions comprising stapled peptides, methods of making same, pharmaceutical compositions comprising same, and methods of treating various diseases, including, but not limited to, metabolic disorders such as diabetes, and cancers. The disclosed compounds comprise stapled peptides, including, but not limited to, stapled glucagon, axin, and p53 peptide homologues, which are useful as therapeutic agents for a variety of diseases as disclosed herein. The disclosed methods are useful in the preparation of a variety of stapled peptides, including stapled peptide homologues of glucagon, axin, and p53. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


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