The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
Apr. 07, 2017
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Nathanael S. Gray, Boston, MA (US);
Tinghu Zhang, Brookline, MA (US);
Fleur M. Ferguson, Cambridge, MA (US);
Jean Zhao, Boston, MA (US);
Jing Ni, Boston, MA (US);
Assignee:
DANA-FARBER CANCER INSTITUTE, INC., Boston, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 487/14 (2006.01); C07D 473/34 (2006.01); A61K 31/551 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/551 (2013.01);
Abstract
The present invention relates to use of pyrimido-diazepinone compounds that are able to modulate protein kinases such as PI3K-γ and PI3K-δ, which are members of the Class I Type IA and Class I Type IB family of phosphatidylinositol-4,5-bisphosphate 3-kinases, and the use of such compounds in the treatment of various diseases, disorders or conditions.