The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
May. 17, 2018
Applicant:
Jiangsu Hengrui Medicine Co., Ltd., Jiangsu, CN;
Inventors:
Assignee:
Jiangsu Hengrui Medicine Co., Ltd., Jiangsu, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/14 (2006.01); A61K 31/4545 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); A61K 31/4545 (2013.01);
Abstract
This application describes a crystal of a benzofuran derivative free base and a preparation method. Specifically, this application describes crystal A, crystal B, crystal C, and crystal D of N-((4,6-dimethyl-2-carbonyl-1,2-dihydropyridin-3-yl)methyl)-5-ethyl-6-(ethyl(tetrahydro-2H-pyran)4-yl)amino)-2-(piperidin-1-ylmethyl)benzofuran-4-carboxamide and a preparation method for the crystals. The crystals of the compound of formula (I) have great crystal stability and provides improved uses in clinical treatment.