The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2021

Filed:

Feb. 25, 2019
Applicant:

Life Technologies Corporation, Carlsbad, CA (US);

Inventors:

Colin Brenan, Marblehead, MA (US);

Jamie Cho, Stoughton, MA (US);

Javier Garcia, Lexington, MA (US);

Robert Hess, Walnut Creek, CA (US);

Tanya Kanigan, Charlotte, VT (US);

Arrin Katz, Cambridge, MA (US);

Namyong Kim, Palo Alto, CA (US);

John Linton, Concord, MA (US);

Shailesh Srivastava, Medway, MA (US);

Karl Yoder, Stoneham, MA (US);

Assignee:

LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J 19/00 (2006.01); B01L 3/00 (2006.01); B01L 3/02 (2006.01);
U.S. Cl.
CPC ...
B01J 19/0046 (2013.01); B01L 3/50857 (2013.01); B01J 2219/0059 (2013.01); B01J 2219/00596 (2013.01); B01J 2219/00659 (2013.01); B01L 3/0244 (2013.01); B01L 3/5025 (2013.01); B01L 2200/12 (2013.01); B01L 2200/16 (2013.01); B01L 2300/16 (2013.01);
Abstract

A differentially coated device for conducting a plurality of nano-volume specified reactions, the device comprising a platen having at least one exterior surface modified to a specified physicochemical property, a plurality of nano-volume channels, each nanovolume channel having at least one interior surface in communication with the at least one exterior surface. Methods for preparing and using such devices are also provided, as well as a method of registering a location of a dispenser array in relation to a microfluidic array. Quantities related to a vector displacement from the alignment position to a fixed position on the one of the dispenser array and the microfluidic array is determined. The quantities thus determined are used to guide positioning of the dispenser array relative to the microfluidic array.


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