The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2021

Filed:

Dec. 17, 2018
Applicants:

University of Southern California, Los Angeles, CA (US);

California Institute of Technology, Pasadena, CA (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

Mark S. Humayun, Glendale, CA (US);

Ashish Ahuja, Los Angeles, CA (US);

Yu-Chong Tai, Pasadena, CA (US);

David R. Hinton, Venice, CA (US);

Robert H. Grubbs, South Pasadena, CA (US);

Dennis O. Clegg, Ventura, CA (US);

Lincoln Vallance Johnson, Santa Barbara, CA (US);

Sherry T. Hikita, Pleasanton, CA (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); A61L 27/18 (2006.01); A61K 35/30 (2015.01); A61L 27/38 (2006.01); A61K 35/545 (2015.01); A61P 27/00 (2006.01); C12N 5/079 (2010.01); A61L 27/34 (2006.01); A61K 9/00 (2006.01); A61L 27/56 (2006.01);
U.S. Cl.
CPC ...
A61L 27/18 (2013.01); A61K 9/0051 (2013.01); A61K 35/30 (2013.01); A61K 35/545 (2013.01); A61K 47/34 (2013.01); A61L 27/34 (2013.01); A61L 27/3808 (2013.01); A61L 27/3813 (2013.01); A61L 27/3834 (2013.01); A61L 27/56 (2013.01); A61P 27/00 (2018.01); C12N 5/0621 (2013.01); A61L 2430/00 (2013.01); A61L 2430/16 (2013.01); C12N 2533/30 (2013.01); C12N 2535/00 (2013.01); Y10T 428/24479 (2015.01);
Abstract

Disclosed herein are substrates for cell delivery to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide seeded cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.


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