The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
Feb. 20, 2018
Applicant:
Creighton University, Omaha, NE (US);
Inventors:
Igor Meerovich, Omaha, NE (US);
Alekha Dash, Omaha, NE (US);
Michael Nichols, Omaha, NE (US);
David Smith, Omaha, NE (US);
Assignee:
Creighton University, Omaha, NE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2020.01); A61K 47/69 (2017.01); A61K 47/64 (2017.01); A61K 47/54 (2017.01); A61K 49/00 (2006.01); A61K 33/243 (2019.01); A61K 31/35 (2006.01); A61K 31/40 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0057 (2013.01); A61K 33/243 (2019.01); A61K 41/0042 (2013.01); A61K 47/546 (2017.08); A61K 47/6455 (2017.08); A61K 47/6911 (2017.08); A61K 49/005 (2013.01); A61K 31/35 (2013.01); A61K 31/40 (2013.01); A61K 2300/00 (2013.01);
Abstract
Provided herein is a small molecule delivery system with illumination-induced small molecule release based on the binary combination of charged liposomes containing small molecules and oppositely charged conjugates of a peptide with a photosensitizer attached to one end of peptide chain, providing binding to liposomes and their permeabilization upon light illumination.