The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
Jan. 08, 2018
Applicant:
Microvax, Llc, Warrenton, VA (US);
Inventor:
Albert B. Deisseroth, Potomac, MD (US);
Assignee:
MicroVAX, LLC, Warrenton, VA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); C07K 14/195 (2006.01); C07K 14/705 (2006.01); C07K 14/47 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/02 (2013.01); C07K 14/195 (2013.01); C07K 14/4702 (2013.01); C07K 14/70575 (2013.01); A61K 2039/53 (2013.01); A61K 2039/6031 (2013.01); C07K 2319/00 (2013.01);
Abstract
A cDNA composition for reducing the virulence of Bp and reduce the cell kill and scope of the infectious disease. (Bp), which encodes fusion proteins comprised of fragments of the extracellular domains of two Bp proteins are attached to the extracellular domain (ecd) of the potent immunostimulatory protein CD40 ligand (CD40L) in order to increase the levels of neutralizing antibodies which will interfere with the function of the extracellular domains of three Bp protein peptide fragments, OMP85, VgrG5 and Hcp-1, in order to protect against a lethal challenge of Bp.