The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
May. 17, 2016
Applicant:
Oncoqr ML Gmbh, Tullnerbach, AT;
Inventors:
Geert Mudde, Breitenfurt, AT;
Jorge Sepulveda, Vienna, AT;
Christopher Taus, Vienna, AT;
Liesbeth Mudde-Boer, Breitenfurt, AT;
Assignee:
ONCOQR ML GMBH, Tullnerbach, AT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/001106 (2018.08); A61K 39/39 (2013.01); A61P 35/00 (2018.01); A61K 2039/505 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/622 (2013.01);
Abstract
The invention provides for an immunogenic composition comprising a. a directed adjuvant comprising at least an anti-CD32 moiety linked to a TLR9 ligand and a first peptidic alpha-helix; and b. an immunogen comprising an extracellular Her2/neu domain that is linked to a second peptidic alpha-helix coiled to the first alpha-helix; The invention further provides a kit for producing such immunogenic composition, a vaccine comprising such immunogenic composition and its medical use, such as for treating Her2/neu positive tumor diseases.