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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11154589 B1

PDFFull Text
Date of Patent:
Oct. 26, 2021

Filed:

Nov. 02, 2017

Antimicrobial composition combinations comprising star shaped peptide polymers

Applicant:

The University of Melbourne, Melbourne, AU;

Inventors:

Greg GuangHua Qiao, Melbourne, AU;

Neil Martin O'Brien-Simpson, Melbourne, AU;

Shu Jie Lam, Melbourne, AU;

Eric Charles Reynolds, Melbourne, AU;

Assignee:

The University of Melbourne, Parkville, AU;

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Thomas S Heard

Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61P 31/04 (2006.01); A61K 38/12 (2006.01); A61K 38/14 (2006.01); A61K 38/02 (2006.01); A61K 31/7056 (2006.01); A61K 31/635 (2006.01); A61K 31/43 (2006.01); A61K 31/7052 (2006.01); A61K 31/437 (2006.01); A61K 31/422 (2006.01); A61K 31/546 (2006.01); A61K 31/496 (2006.01); A61K 31/7048 (2006.01); A61K 31/7036 (2006.01); A61K 31/4375 (2006.01); A61K 31/407 (2006.01); A61K 31/65 (2006.01);
U.S. Cl.
CPC ...
A61K 38/16 (2013.01); A61K 31/407 (2013.01); A61K 31/422 (2013.01); A61K 31/43 (2013.01); A61K 31/437 (2013.01); A61K 31/4375 (2013.01); A61K 31/496 (2013.01); A61K 31/546 (2013.01); A61K 31/635 (2013.01); A61K 31/65 (2013.01); A61K 31/7036 (2013.01); A61K 31/7048 (2013.01); A61K 31/7052 (2013.01); A61K 31/7056 (2013.01); A61K 38/02 (2013.01); A61K 38/12 (2013.01); A61K 38/14 (2013.01); A61P 31/04 (2018.01);
Abstract

This invention relates to compositions including antibacterial compounds. The invention also relates to the use of the compositions in methods of treating bacterial infections. In one aspect the present invention also provides a method of increasing the susceptibility of bacteria to the anti-bacterial activity of a compound, the method comprising contacting the bacteria with a star shaped peptide polymer of the invention, thereby increasing the susceptibility of the bacteria to the anti-bacterial activity of the compound. Preferably, the method further includes the step of contacting the bacteria with the compound for which the bacteria have increased susceptibility to. The invention is further relates to the combination of a star shaped peptide polymer and an anti-bacterial compound that restore the sensitivity of antibiotic resistant bacteria to antibiotics that are otherwise ineffective when administered alone.

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