The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
Apr. 30, 2015
Jiangsu University, Jiangsu, CN;
Shengjun Wang, Jiangsu, CN;
Yungang Wang, Jiangsu, CN;
Jie Tian, Jiangsu, CN;
Ke Rui, Jiangsu, CN;
Jie Ma, Jiangsu, CN;
Bin Ma, Jiangsu, CN;
Xinyi Tang, Jiangsu, CN;
Huaxi Xu, Jiangsu, CN;
JIANGSU UNIVERSITY, Jiangsu, CN;
Abstract
Provided are exosomes sourced from a granulocyte myeloid-derived suppressor cell and an application thereof. The exosomes are named as G-MDSC exo. Also provided is a use of the exosomes in preparing a drug used for suppressing autoimmune diseases. The G-MDSC exo can effectively suppress proliferation of CD4+T cells in vitro, promote induced proliferation of T regulatory (Treg) cells, alleviate foot swelling of model mice having delayed-type hypersensitivity, and suppress attacks of inflammatory bowel disease (IBD) and collagen-induced arthritis (CIA) of the mice.