The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2021
Filed:
Oct. 20, 2017
Applicant:
Sareum Limited, Cambridge, GB;
Inventor:
John Charles Reader, Cambridge, GB;
Assignee:
Sareum Limited, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/422 (2006.01); A61K 31/421 (2006.01); A61P 35/00 (2006.01); A61K 31/454 (2006.01); A61K 31/5377 (2006.01); A61K 31/675 (2006.01);
U.S. Cl.
CPC ...
A61K 31/421 (2013.01); A61K 31/422 (2013.01); A61K 31/454 (2013.01); A61K 31/5377 (2013.01); A61P 35/00 (2018.01); A61K 31/675 (2013.01);
Abstract
The invention provides a compound for use in the treatment of T-Cell Acute Lymphoblastic Leukaemia (T-ALL), the compound having the formula (1): or being a pharmaceutically acceptable salt thereof; wherein:n is 0, 1 or 2;Aris selected from an optionally substituted phenyl, pyridyl, thienyl and furanyl;Qis selected from C(═O), S(═O) and SO;A is absent or is NR;Ris selected from: