The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 19, 2021

Filed:

Apr. 15, 2016
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Peter Robinson, Berkeley, CA (US);

Cheng-Ting Tsai, Berkeley, CA (US);

Carolyn Bertozzi, Stanford, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6804 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/686 (2018.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6804 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/686 (2013.01); G01N 33/54306 (2013.01); C12Q 2525/117 (2013.01); C12Q 2525/155 (2013.01); C12Q 2525/197 (2013.01); C12Q 2531/113 (2013.01);
Abstract

Methods are provided for detecting antigen binding agents in samples. Aspects of the methods include detection of the aggregation of antigen binding agents with polynucleotide-bound antigens by sensitive proximity-based association of the antigen-bound polynucleotides. Aspects of the methods also include methods for the detection of such proximity-based association through nucleic acid amplification. In addition, compositions, e.g., reagents, kits, and devices, useful in practicing various embodiments of the methods are provided.


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