The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Oct. 09, 2017
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Florin M. Selaru, Catonsville, MD (US);
Stephen J. Meltzer, Lutherville, MD (US);
George L. Coles, Baltimore, MD (US);
Honggang Cui, Lutherville, MD (US);
Assignee:
THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C12N 15/113 (2010.01); A61P 35/00 (2006.01); A61K 47/46 (2006.01); A61K 9/00 (2006.01); A61K 9/48 (2006.01); A61K 47/42 (2017.01); A61K 9/70 (2006.01); A61K 9/50 (2006.01); A61K 9/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 9/0053 (2013.01); A61K 9/4808 (2013.01); A61K 47/46 (2013.01); A61P 35/00 (2018.01); C12N 15/113 (2013.01); A61K 9/0065 (2013.01); A61K 9/06 (2013.01); A61K 9/5068 (2013.01); A61K 9/70 (2013.01); A61K 47/42 (2013.01); C12N 2310/141 (2013.01); C12N 2320/32 (2013.01);
Abstract
Described are devices for treating disease in subjects wherein the devices include a sponge comprising a hydrogel, extracellular vesicles (EVs), and an agent. Methods of using the devices to treat or prevent disease such as esophageal adenocarcinoma are also described.