The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Sep. 06, 2017
Applicants:
Bioventures, Llc, Little Rock, AR (US);
The Research Foundation for the State University of New York, Albany, NY (US);
Inventors:
James Forrest, Little Rock, AR (US);
Gang Li, Little Rock, AR (US);
Laurie Krug, Albany, NY (US);
Steven Skiena, Albany, NY (US);
Assignees:
BioVentures, LLC, Little Rock, AR (US);
The Research Foundation for the State of University of New York, Albany, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12N 7/04 (2006.01); C12N 15/86 (2006.01); A61P 31/22 (2006.01); A61K 39/12 (2006.01); A61K 39/245 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 39/12 (2013.01); A61K 39/245 (2013.01); A61P 31/22 (2018.01); C12N 7/04 (2013.01); C12N 15/86 (2013.01); A61K 2039/5254 (2013.01); C12N 2710/16034 (2013.01); C12N 2710/16043 (2013.01); C12N 2710/16062 (2013.01); C12N 2710/16434 (2013.01); C12N 2710/16443 (2013.01); C12N 2710/16452 (2013.01); C12N 2740/10043 (2013.01);
Abstract
Provided herein are methods for generating reversion free attenuated and/or replication incompetent vaccine vectors and their use in vaccine compositions and vaccination. In particular, the use of a codon shuffled helper gene is used to produce compositions comprising replication incompetent virus.