The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Jun. 19, 2019
Applicant:
Albert Einstein College of Medicine, Bronx, NY (US);
Inventors:
Kartik Chandran, Brooklyn, NY (US);
Anna Z. Wec, Bronx, NY (US);
Elisabeth K. Nyakatura, New York, NY (US);
Jonathan R. Lai, Dobbs Ferry, NY (US);
Assignee:
Albert Einstein College of Medicine, Bronx, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/10 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/46 (2006.01); A61P 31/14 (2006.01);
U.S. Cl.
CPC ...
C07K 16/10 (2013.01); A61K 39/00 (2013.01); A61K 39/395 (2013.01); A61P 31/14 (2018.01); C07K 16/28 (2013.01); C07K 16/468 (2013.01); C07K 2317/31 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01); C07K 2319/01 (2013.01); C12N 2760/14111 (2013.01);
Abstract
Disclosed are bispecific antibodies and bispecific fusion constructs that bind to Niemann-Pick C1 (NPC1) receptor for treating or preventing filovirus infections, pharmaceutical compositions comprising the bispecific antibodies, and therapeutic methods using the bispecific antibodies.