The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Aug. 26, 2015
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Jason C. O'Neill, Brier, WA (US);
Randal R. Ketchem, Snohomish, WA (US);
Taeweon Lee, Palo Alto, CA (US);
Vishnu Chintalgattu, Union City, CA (US);
Jennitte Leann Stevens, Thousand Oaks, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/81 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/8146 (2013.01); A61K 38/00 (2013.01);
Abstract
The application concerns tissue inhibitor of metalloproteinase 3 (TIMP-3) muteins, variants and derivatives, nucleic acids encoding them, and methods of making and using them; in particular, muteins of TIMP-3 with specific amino acid substitutions in order to introduce N-linked glycosylation sites.