The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Feb. 17, 2017
Applicants:
Wilfred Chen, Hockessin, DE (US);
Andrew Swartz, Newark, DE (US);
Inventors:
Wilfred Chen, Hockessin, DE (US);
Andrew Swartz, Newark, DE (US);
Assignee:
University of Delaware, Newark, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/32 (2006.01); C07K 1/22 (2006.01); B82Y 5/00 (2011.01); C07K 14/78 (2006.01); C12N 9/02 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
C07K 1/32 (2013.01); B82Y 5/00 (2013.01); C07K 1/22 (2013.01); C07K 14/78 (2013.01); C12N 9/0008 (2013.01); C12N 9/6472 (2013.01); C07K 2319/00 (2013.01); C07K 2319/01 (2013.01); C07K 2319/70 (2013.01); C12Y 101/01081 (2013.01); C12Y 304/2207 (2013.01);
Abstract
The present invention provides a nanoparticle capable of binding specifically to a target protein in a solution and precipitating with the target protein out of the solution upon addition of the target protein to the solution. The precipitation may be reversed release the target protein from the nanoparticle, which may be reused for precipitating the target protein. Also provided are a method for purifying a target protein by affinity precipitation using the nanoparticle without chromatography and a method for preparing the nanoparticle.