The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Oct. 25, 2018
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Paul John Dransfield, Arlington, MA (US);
James S. Harvey, Arlington, MA (US);
Zhihua Ma, Lexington, MA (US);
Ankit Sharma, Quincy, MA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 498/04 (2006.01); C07D 498/14 (2006.01); A61K 31/395 (2006.01); A61K 31/553 (2006.01); A61P 9/00 (2006.01); C07F 7/08 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61P 9/00 (2018.01); C07D 487/04 (2013.01); C07D 498/14 (2013.01); C07F 7/0812 (2013.01); A61K 45/06 (2013.01);
Abstract
Compounds of Formula I, pharmaceutically acceptable salts thereof, tautomers thereof, pharmaceutically acceptable salts of the tautomers, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula (I) have the following structure: where the definitions of the variables are provided herein.