The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Jun. 11, 2018
Glaxosmithkline Intellectual Property Development Limited, Middlesex, GB;
David Norman Deaton, Collegeville, PA (US);
Barry George Shearer, Collegeville, PA (US);
Mark Andrew Youngman, Collegeville, PA (US);
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DFVELOPMENT LIMITED, Middlesex, GB;
Abstract
A compound of formula (I) wherein R, R, R, R, X, Y, and A are as defined herein. The compounds of the present invention are inhibitors of hematopoletic prostaglandin D synthase (H-PGDS) and can be useful in the treatment of Duchenne muscular dystrophy. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting H-PGDS activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.