The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
May. 16, 2019
Sanofi, Paris, FR;
Monsif Bouaboula, Bridegwater, NJ (US);
Maurice Brollo, Paris, FR;
Victor Certal, Paris, FR;
Youssef El-Ahmad, Paris, FR;
Bruno Filoche-Romme, Paris, FR;
Frank Halley, Paris, FR;
Gary McCort, Paris, FR;
Laurent Schio, Paris, FR;
Michel Tabart, Paris, FR;
Corinne Terrier, Paris, FR;
Fabienne Thompson, Paris, FR;
Sanofi, Paris, FR;
Abstract
The present disclosure relates to novel substituted N-(3-fluoropropyl)-pyrrolidine compounds of formula (I-A), wherein R1 and R2 represent independently a hydrogen atom or a deuterium atom; A represents an oxygen or nitrogen atom; and SERM-F represents a selective estrogen receptor modulator fragment comprising an aryl or heteroaryl group linked to the adjacent 'A' group. The disclosure also relates to the preparation and to the therapeutic uses of the compounds of formula (I-A) as inhibitors and degraders of estrogen receptors.