The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Dec. 15, 2017
Nova Southeastern University, Fort Lauderdale, FL (US);
Auburn University, Auburn, AL (US);
Florida Atlantic University Board of Trustees, Boca Raton, FL (US);
Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL (US);
Dmitriy Minond, Fort Lauderdale, FL (US);
Gregg B. Fields, Boca Raton, FL (US);
Marcello Giulianotti, Port St. Lucie, FL (US);
Nova Southeastern University, Fort Lauderdale, FL (US);
Auburn University, Auburn, AL (US);
Florida Atantic University Board Of Trustees, Boca Raton, FL (US);
Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL (US);
Abstract
The invention provides methods for treating cancers, such as melanoma and/or metastatic melanoma, using compounds that interact with and/or inhibit cellular proteins lamin A/C, ATP-dependent RNA helicase DDX1 (DDX1), heterogeneous nuclear ribonuclear protein H1/H2 (hnRNP H2), and/or heterogeneous nuclear ribonuclear protein A2/B1 (hnRNP A2/B1). The invention additionally provides a method for identifying compounds active against melanoma cells.