The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Sep. 07, 2018
Msn Laboratories Private Limited, R&d Center, Telangan, IN;
Thirumalai Rajan Srinivasan, Hyderabad, IN;
Eswaraiah Sajja, Hyderabad, IN;
Venkat Reddy Ghojala, Hyderabad, IN;
Rajeshwar Reddy Sagyam, Hyderabad, IN;
Srinivasulu Rangineni, Hyderabad, IN;
Rajashekar Kommera, Hyderabad, IN;
Markandeya Bekkam, Hyderabad, IN;
MSN LABORATORIES PRIVATE LIMITED, R&D CENTER, Telangana, IN;
Abstract
The present invention relates to solid state forms of 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4-(1H,3H)-dione hydrochloride compound of formula-1a and their processes for the preparation thereof and an improved process for the preparation of 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4-(1H,3H)-dione hydrochloride. The present inventors also provides an amorphous polymorph of the combination drug consisting of 2'-deoxy-5-(trifluoromethyl) uridine and 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4-(1H,3H)-dione monohydrochloride and its process for the preparation.