The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Dec. 29, 2016
Applicant:
Hitgen Ltd., Sichuan, CN;
Inventors:
Jin Li, Sichuan, CN;
Xueming Li, Sichuan, CN;
Dengfeng Dou, Sichuan, CN;
Jinqiao Wan, Sichuan, CN;
Wei Zhang, Sichuan, CN;
Jingming Li, Sichuan, CN;
Yan Lan, Sichuan, CN;
Linli Li, Sichuan, CN;
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/96 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 411/12 (2006.01); A61P 35/00 (2006.01); A61K 31/44 (2006.01); C07D 211/78 (2006.01);
U.S. Cl.
CPC ...
C07D 211/96 (2013.01); A61K 31/44 (2013.01); A61P 35/00 (2018.01); C07D 211/78 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 411/12 (2013.01);
Abstract
The present invention discloses a compound shown in formula I or a stereoisomer, pharmaceutically acceptable salt, crystal form, solvate or isotopologue thereof. The compound of the present invention shows excellent inhibition activity against histone deacetylases, has remarkable inhibition effects on cancer cells, and provides a new choice of drugs used for the clinic treatment and diseases related to the abnormal activity of histone deacetylases.