logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11149002 B1

PDFFull Text
Date of Patent:
Oct. 19, 2021

Filed:

Dec. 03, 2019

Therapeutic compounds and methods of use thereof

Applicants:

Genentech, Inc., South San Francisco, CA (US);

Xenon Pharmaceuticals Inc., Burnaby, CA;

Inventors:

Jean-Christophe Andrez, Burnaby, CA;

Philippe Bergeron, South San Francisco, CA (US);

Paul Robert Bichler, Burnaby, CA;

Sultan Chowdhury, Burnaby, CA;

Christoph Martin Dehnhardt, Burnaby, CA;

Thilo Focken, Burnaby, CA;

Wei Gong, Burnaby, CA;

Michael Edward Grimwood, Burnaby, CA;

Abid Hasan, Burnaby, CA;

Ivan William Hemeon, Burnaby, CA;

Qi Jia, Burnaby, CA;

Brian Salvatore Safina, South San Francisco, CA (US);

Shaoyi Sun, Burnaby, CA;

Michael Scott Wilson, Burnaby, CA;

Alla Yurevna Zenova, Burnaby, CA;

Assignees:

GENENTECH, INC., South San Francisco, CA (US);

XENON PHARMACEUTICALS INC., Burnaby, CA;

Attorney:

Viksnins Harris Padys Malen LLP

Primary Examiner:

Heidi Reese

Int. Cl.
CPC ...
C07D 207/16 (2006.01); C07D 403/12 (2006.01); C07D 413/14 (2006.01); C07D 221/22 (2006.01); C07D 401/12 (2006.01); C07D 413/12 (2006.01); C07C 235/52 (2006.01); C07D 205/04 (2006.01); C07D 277/06 (2006.01); C07D 209/02 (2006.01); C07D 305/08 (2006.01); C07D 401/14 (2006.01); C07D 231/06 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 409/06 (2006.01); C07D 417/12 (2006.01); C07D 451/02 (2006.01); C07D 263/04 (2006.01); C07D 263/26 (2006.01); C07C 235/42 (2006.01); C07C 235/54 (2006.01); C07D 265/30 (2006.01); C07D 207/08 (2006.01); C07D 207/10 (2006.01); C07D 207/22 (2006.01); C07D 209/52 (2006.01); C07D 209/54 (2006.01); C07D 211/20 (2006.01); C07D 211/38 (2006.01); C07D 211/60 (2006.01); C07D 213/69 (2006.01); C07D 401/10 (2006.01); C07D 405/10 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
C07D 207/16 (2013.01); C07C 235/42 (2013.01); C07C 235/52 (2013.01); C07C 235/54 (2013.01); C07D 205/04 (2013.01); C07D 207/08 (2013.01); C07D 207/10 (2013.01); C07D 207/22 (2013.01); C07D 209/02 (2013.01); C07D 209/52 (2013.01); C07D 209/54 (2013.01); C07D 211/20 (2013.01); C07D 211/38 (2013.01); C07D 211/60 (2013.01); C07D 213/69 (2013.01); C07D 221/22 (2013.01); C07D 231/06 (2013.01); C07D 263/04 (2013.01); C07D 263/26 (2013.01); C07D 265/30 (2013.01); C07D 277/06 (2013.01); C07D 305/08 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/10 (2013.01); C07D 409/06 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 451/02 (2013.01); C07D 471/08 (2013.01); C07C 2601/02 (2017.05); C07C 2601/04 (2017.05); C07C 2603/74 (2017.05);
Abstract

The invention provides compounds having the general Formula (I); and pharmaceutically acceptable salts thereof; wherein the variables R, R, subscript n, subscript q, ring A, X, L, subscript m, X, R, R, R, R, R, D and E have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

Find Patent Forward Citations

Loading…