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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11148998 B1

PDFFull Text
Date of Patent:
Oct. 19, 2021

Filed:

May. 23, 2018

Dimethyl-nonatetraenyl-trimethyl-cyclohexyl compounds and uses thereof

Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

James Varani, Ann Arbor, MI (US);

Hollis Showalter, Ann Arbor, MI (US);

Andy White, Ann Arbor, MI (US);

Kent J. Johnson, Ann Arbor, MI (US);

Assignee:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Attorneys:

Casimir Jones, S.C.

Robert A. Goetz

Primary Examiner:

Samantha L Shterengarts

Int. Cl.
CPC ...
A61K 45/06 (2006.01); C07C 235/30 (2006.01); C07D 209/54 (2006.01); C07D 305/06 (2006.01); C07C 233/50 (2006.01); C07C 233/31 (2006.01); C07D 211/74 (2006.01); C07D 207/24 (2006.01); A61P 17/10 (2006.01); A61P 17/06 (2006.01); A61P 35/02 (2006.01); A61P 17/02 (2006.01);
U.S. Cl.
CPC ...
C07C 235/30 (2013.01); A61P 17/02 (2018.01); A61P 17/06 (2018.01); A61P 17/10 (2018.01); A61P 35/02 (2018.01); C07C 233/31 (2013.01); C07C 233/50 (2013.01); C07D 207/24 (2013.01); C07D 209/54 (2013.01); C07D 211/74 (2013.01); C07D 305/06 (2013.01); A61K 45/06 (2013.01); A61K 2300/00 (2013.01); C07C 2601/02 (2017.05); C07C 2601/16 (2017.05);
Abstract

This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a dimethyl-nonatetraenyl-trimethyl-cyclohexyl structure useful as therapeutics for the treatment of subjects suffering from disorders characterized by abnormal proliferation and/or abnormal differentiation of cells, in particular of cells of which the growth and differentiation is sensitive to the actions of retinoids.

Find Patent Forward Citations

Varani, James. (2021). Dimethyl-nonatetraenyl-trimethyl-cyclohexyl compounds and uses thereof (U.S. Patent No. 11148998). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11148998

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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