The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Sep. 02, 2014
Applicants:
Technion Research & Development Foundation Limited, Haifa, IL;
Health Corporation-rambam, Haifa, IL;
Inventors:
Shulamit Levenberg, Moreshet, IL;
Dana Egozi, Haifa, IL;
Jacob Koffler, Tel-Aviv, IL;
Yulia Shandalov-Levi, Haifa, IL;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/18 (2006.01); C12N 5/077 (2010.01); A61L 27/36 (2006.01); A61L 27/56 (2006.01); A61L 27/38 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
A61L 27/18 (2013.01); A61L 27/3625 (2013.01); A61L 27/3695 (2013.01); A61L 27/3808 (2013.01); A61L 27/3886 (2013.01); A61L 27/3895 (2013.01); A61L 27/56 (2013.01); C12N 5/069 (2013.01); C12N 5/0658 (2013.01); A61L 2300/64 (2013.01); A61L 2430/34 (2013.01); C12N 2502/13 (2013.01); C12N 2502/1335 (2013.01); C12N 2533/40 (2013.01);
Abstract
The present invention provides an implant which includes: (a) an autologous engineered tissue; and (b) a vasculature, wherein the engineered tissue is a porous scaffold embedded with endothelial cell, a fibroblast, a myoblast, a mesenchymal cell, an adipocyte, or any combination thereof, wherein the vasculature feeds the cells. Further, the invention provides a method for treating a subject afflicted with a large soft tissue defect by implanting the implant of the invention.