The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 19, 2021

Filed:

Jan. 05, 2017
Applicant:

Shenzhen Targetrx, Inc., Shenzhen, CN;

Inventors:

Yihan Wang, Shenzhen, CN;

Huanyin Li, Shenzhen, CN;

Assignee:

Shenzhen TargetRx, Inc., Guangdong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4245 (2006.01); C07D 285/01 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); C07D 271/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4245 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 271/08 (2013.01); C07B 2200/05 (2013.01); C07B 2200/13 (2013.01);
Abstract

Provided are a substituted oxadiazole chemical compound and composition containing said chemical compound and use thereof; said substituted oxadiazole chemical compound is the oxadiazole chemical compound as represented by formula (I), or its crystalline form, pharmaceutically acceptable salt, prodrug, stereoisomer, hydrate, or solvent compound. The disclosed substituted oxadiazole chemical compound and composition containing said chemical compound are capable of inhibiting indoleamine 2,3-dioxygenase; it also has better pharmacokinetic parameter attributes and is capable of improving the drug concentration of the chemical compound in an animal body, thus improving the therapeutic efficacy and safety of the drug.


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